他汀類酮基還原酶

產品描述

酮基還原酶是一種通過基因工程手段，采用高通量篩選技術，以大腸桿菌為表達載體，經培養、深層 發酵、提取、多次過濾和純化精制而成的能夠特異性作用于羰基類化合物的酶制劑產品。

產品特性

  最適作用pH為6.5~7.5,在pH=6.0~8.0范圍內穩定。

  最適作用溫度為30℃。

  固體冰塊， 融化后為灰白色至灰色渾濁液體.

應用范圍

  降血酯類(阿托伐他汀、瑞蘇伐他汀)醫藥中間體酶法合成；

  平喘類藥(沙丁胺醇)、抗抑郁藥物(托莫西汀、氟西汀、度洛西汀)中間體酶法合成；   農藥及其他精細化工原料中間體酶法合成。

Statin ketone reductase product description ketone reductase is a gene engineering method, using high-throughput screening technology, with E. coli as the expression vector, after culture, deep layer, an enzyme product produced by fermentation, extraction, multiple filtration, and purification that acts specifically on carbonyl compounds. The optimum pH is 6.5 ~ 7.5, stable in the range of pH = 6.0 ~ 8.0. The optimum temperature is 30 °C. Solid ice that melts into a grayish-white to grayish cloudy liquid. Scope of application: enzymatic synthesis of pharmaceutical intermediates of Atorvastatin; Enzymatic synthesis of intermediates of antiasthmatic drugs (salbutamol) and antidepressants (atomoxetine, fluoxetine, Duloxetine) , pesticides and other fine chemicals.